CARDIOVASCULAR EFFECTS OF ONE YEAR OF ALAGEBRIUM AND ENDURANCE EXERCISE TRAINING IN HEALTHY OLDER INDIVIDUALS
نویسندگان
چکیده
منابع مشابه
Cardiovascular effects of 1 year of alagebrium and endurance exercise training in healthy older individuals.
BACKGROUND Lifelong exercise training maintains a youthful compliance of the left ventricle (LV), whereas a year of exercise training started later in life fails to reverse LV stiffening, possibly because of accumulation of irreversible advanced glycation end products. Alagebrium breaks advanced glycation end product crosslinks and improves LV stiffness in aged animals. However, it is unclear w...
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15 صفحه اولExercise Physiology Cardiovascular Effects of 1 Year of Progressive and Vigorous Exercise Training in Previously Sedentary Individuals Older Than 65 Years of Age
Background—Healthy but sedentary aging leads to cardiovascular stiffening, whereas life-long endurance training preserves left ventricular (LV) compliance. However, it is unknown whether exercise training started later in life can reverse the effects of sedentary behavior on the heart. Methods and Results—Twelve sedentary seniors and 12 Masters athletes were thoroughly screened for comorbiditie...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2013
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(13)61257-7